Brief Information of the Compound and Protein
Compound Name
(2R)-2-({5-Chloro-4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]-6-[(2-morpholin-4-ylethyl)amino] pyrimidin-2-yl}amino)-2-(4-fluorophenyl)ethanol
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PubChem ID
CID: 24949553
SID: 56247335
Canonical SMILES
OC[C@H](Nc1nc(NCCN2CCOCC2)c(Cl)c(Nc2cc(C3CC3)[nH]n2)n1)c1ccc(F)cc1
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Compound Formula C24H30ClFN8O2
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 12 nM
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