Brief Information of the Compound and Protein
Compound Name
N'-(5-Cyclopropyl-2H-pyrazol-3-yl)-N-[(1S)-1-(4-fluorophenyl-)ethyl]-5-methylpyrimidine-2,4-diamine
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PubChem ID
CID: 24949403
SID: 56247185
Canonical SMILES
Cc1cnc(N[C@@H](C)c2ccc(F)cc2)nc1Nc1cc(C2CC2)[nH]n1
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Compound Formula C19H21FN6
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
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Kinase
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Protein Kinase
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TK protein kinase group
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Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 10 nM
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