Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2-Methoxy-5-trifluoromethoxy-benzyl)-((2S,3S)-2-phenyl-piperidin-3-yl)-amine
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 PubChem ID
CID: 9821217
SID: 14780102
Canonical SMILES
COc1ccc(OC(F)(F)F)cc1CN[C@H]1CCCN[C@H]1c1ccccc1
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Compound Formula C20H23F3N2O2
Compound Structure
Protein Name
 Protein Info 
Substance-P receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Neurokinin receptor
Uniprot ID
P25103
Gene Name
TACR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.14 nM
   TI
   LI
   LO
   TS
CL000228 IM-9
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.19 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.4 nM
   TI
   LI
   LO
   TS