Brief Information of the Compound and Protein
Compound Name
(3R,4R,5R)-3,4-dihydroxy-5-(((R)-2-hydroxy-1-phenylethylamino)methyl)-1-methylpyrrolidin-2-one
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PubChem ID
CID: 24832046
SID: 99447989
Canonical SMILES
CN1[C@H](CN[C@@H](CO)c2ccccc2)[C@@H](O)[C@@H](O)C1=O
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Compound Formula C14H20N2O4
Compound Structure
Protein Name
Lysosomal alpha-mannosidase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
O00754
Gene Name
MAN2B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000424 LN-18 Homo sapiens (Human)  2
1
IC50 = 2000 nM
   TI
   LI
   LO
   TS
2
Ki = 3200 nM
   TI
   LI
   LO
   TS
CL000418 LN-308 Homo sapiens (Human)  2
1
IC50 = 500 nM
   TI
   LI
   LO
   TS
2
Ki = 550 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 500 nM
2 Ki = 670 nM