Brief Information of the Compound and Protein
Compound Name
(2R,3R,4S)-2-({[(1R)-2-HYDROXY-1-PHENYLETHYL]AMINO}METHYL)PYRROLIDINE-3,4-DIOL
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PubChem ID
CID: 11425273
SID: 16522362
Canonical SMILES
OC[C@H](NC[C@H]1NC[C@H](O)[C@@H]1O)c1ccccc1
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Compound Formula C13H20N2O3
Compound Structure
Protein Name
Lysosomal alpha-mannosidase
Protein Classification
Enzyme
>
Hydrolase
Uniprot ID
O00754
Gene Name
MAN2B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000424 LN-18 Homo sapiens (Human)  2
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 32500 nM
   TI
   LI
   LO
   TS
CL000418 LN-308 Homo sapiens (Human)  2
1
IC50 = 50000 nM
   TI
   LI
   LO
   TS
2
Ki = 41500 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 25000 nM
2 Ki = 23300 nM