Brief Information of the Compound and Protein
Compound Name
2,8-Dimethyl-3-(4-{[3-(1-pyrrolidinyl)propyl]oxy}phenyl)-4(3H)-quinazolinone
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PubChem ID
CID: 24951192
SID: 56248984
Canonical SMILES
Cc1cccc2c1nc(C)n(-c1ccc(OCCCN3CCCC3)cc1)c2=O
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Compound Formula C23H27N3O2
Compound Structure
Protein Name
Histamine H3 receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Histamine receptor
Uniprot ID
Q9Y5N1
Gene Name
HRH3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
IC50 = 1.7 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.625 nM