Bioactivity Information

Brief Information of the Compound and Protein

Compound Name

Compound Info

5-(4-chloro-3-methyl-phenyl)-1-(4-methyl-benzyl)-1H-pyrazole-3-carboxylic acid (1,3,3-trimethyl-bicyclo[2.2.1]hept-2-yl)-amide

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PubChem ID

CID: 44208932

Canonical SMILES	Cc1ccc(Cn2nc(cc2-c2ccc(Cl)c(C)c2)C(=O)NC2C3(C)CCC(C3)C2(C)C)cc1 Show/Hide
Compound Formula	C29H34ClN3O

Compound Structure

Protein Name

Protein Info

Cannabinoid receptor 1

Protein Classification

Membrane receptor

Family A G protein-coupled receptor

Small molecule receptor (family A GPCR)

Lipid-like ligand receptor (family A GPCR)

Cannabinoid receptor

Uniprot ID

P21554

Gene Name

CNR1

Table of Molecular Bioactivities Related to the Compound and Protein

Cell-based Assay

Cell Line ID	Cell Line Name	Cell Line Organism
CL000011	CHO Cell Line Info	Cricetulus griseus (Chinese hamster)	3
1	Ki = 400 nM	TI LI LO TS
2	Ki > 10000 nM	TI LI LO TS
3	Ki > 1000 nM	TI LI LO TS
CL000006	HEK293 Cell Line Info	Homo sapiens (Human)	4
1	Ki = 437 nM	TI LI LO TS
2	Ki > 2820 nM	TI LI LO TS
3	Ki > 5000 nM	TI LI LO TS
4	Ki > 5600 nM	TI LI LO TS

Biochemical Assays