Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[(2S,3S)-4-(4-chlorophenyl)-3-(3-cyanophenyl)butan-2-yl]-2-methyl-2-[5-(trifluoromethyl)pyridin-2-yl]oxypropanamide
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 PubChem ID
CID: 11226090
SID: 50086932
Canonical SMILES
C[C@H](NC(=O)C(C)(C)Oc1ccc(cn1)C(F)(F)F)[C@@H](Cc1ccc(Cl)cc1)c1cccc(c1)C#N
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Compound Formula C27H25ClF3N3O2
Compound Structure
Protein Name
 Protein Info 
Cannabinoid receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Lipid-like ligand receptor (family A GPCR)
>
Cannabinoid receptor
Uniprot ID
P21554
Gene Name
CNR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
EC50 = 2.4 nM
   TI
   LI
   LO
   TS
2
IC50 = 0.29 nM
   TI
   LI
   LO
   TS
3
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
4
IC50 = 0.74 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 0.3 nM
   TI
   LI
   LO
   TS
2
Ki = 0.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.3 nM