Brief Information of the Compound and Protein
Compound Name
4-(8-methoxy-5,6-dihydrobenzo[h]quinazolin-2-ylamino)benzenesulfonamide
    Show/Hide
PubChem ID
CID: 46871628
SID: 99311248
Canonical SMILES
COc1ccc-2c(CCc3cnc(Nc4ccc(cc4)S(N)(=O)=O)nc-23)c1
    Show/Hide
Compound Formula C19H18N4O3S
Compound Structure
Protein Name
Inhibitor of nuclear factor kappa-B kinase subunit beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
Uniprot ID
O14920
Gene Name
IKBKB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  1
1
IC50 = 420 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 550 nM