Brief Information of the Compound and Protein
Compound Name
1-[6-(4-Fluorophenyl)pyridin-3-yl]-3-(4-piperidin-1-ylbutyl)urea
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PubChem ID
CID: 44240743
SID: 85260669
Canonical SMILES
Fc1ccc(cc1)-c1ccc(NC(=O)NCCCCN2CCCCC2)cn1
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Compound Formula C21H27FN4O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  3
1
EC50 = 70 nM
   TI
   LI
   LO
   TS
2
EC50 = 490 nM
   TI
   LI
   LO
   TS
3
Ki = 44 nM
   TI
   LI
   LO
   TS