Brief Information of the Compound and Protein
Compound Name
(R)-2-(2-methoxypyrimidin-5-yl)-6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinoline
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PubChem ID
CID: 46890430
Canonical SMILES
COc1ncc(cn1)-c1ccc2cc(CCN3CCC[C@H]3C)ccc2n1
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Compound Formula C21H24N4O
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 5600 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22400 nM