Brief Information of the Compound and Protein
Compound Name
(R)-4-(6-(2-(2-methylpyrrolidin-1-yl)ethyl)quinolin-2-yl)-2-(6-(2,2,2-trifluoroethoxy)pyridin-3-yl)thiazole
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PubChem ID
CID: 11663315
SID: 16766969
Canonical SMILES
C[C@@H]1CCCN1CCc1ccc2nc(ccc2c1)-c1csc(n1)-c1ccc(OCC(F)(F)F)nc1
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Compound Formula C26H25F3N4OS
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 380 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1520 nM