Brief Information of the Compound and Protein
Compound Name
 Compound Info 
PF-2545920
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 PubChem ID
CID: 11581936
SID: 16684394
Canonical SMILES
Cn1cc(c(n1)-c1ccc(OCc2ccc3ccccc3n2)cc1)-c1ccncc1
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Compound Formula C25H20N4O
Compound Structure
Protein Name
 Protein Info 
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Protein Classification
Enzyme
>
Phosphodiesterase
>
Phosphodiesterase 10
>
Phosphodiesterase 10A
Uniprot ID
Q9Y233
Gene Name
PDE10A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 1.34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 0.18 nM
2 IC50 = 0.3 nM
3 IC50 = 0.37 nM
4 IC50 = 1.26 nM
5 IC50 = 1.68 nM
6 IC50 = 2.6 nM