Brief Information of the Compound and Protein
Compound Name
3-((2-(2-aminopyrimidin-4-yl)-3-methylbenzo[b]thiophen-5-yl)methyl)phenol
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PubChem ID
CID: 24878398
SID: 50133805
Canonical SMILES
Cc1c(sc2ccc(Cc3cccc(O)c3)cc12)-c1ccnc(N)n1
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Compound Formula C20H17N3OS
Compound Structure
Protein Name
Rho-associated protein kinase 1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase DMPK family
>
AGC protein kinase ROCK subfamily
Uniprot ID
Q13464
Gene Name
ROCK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000333 GTM-3 Homo sapiens (Human)  1
1
EC50 = 2900 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM