Brief Information of the Compound and Protein
Compound Name
3-((5,6-dihydropyridin-1(2H)-yl)methyl)-8-mesityl-2-(trifluoromethyl)-5,6,7,8-tetrahydroimidazo[1,2-a]pyrimidine
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PubChem ID
CID: 21916261
Canonical SMILES
Cc1cc(C)c(N2CCCn3c(CN4CCC=CC4)c(nc23)C(F)(F)F)c(C)c1
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Compound Formula C22H27F3N4
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
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Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Corticotropin releasing factor receptor
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Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000016 IMR-32 Homo sapiens (Human)  1
1
Ki = 364 nM
   TI
   LI
   LO
   TS