Brief Information of the Compound and Protein
Compound Name
2-[2-Methyl-3-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridin-1-yl]ethylamine
    Show/Hide
PubChem ID
CID: 45484381
Canonical SMILES
Cc1c(c2cccnc2n1CCN)S(=O)(=O)c1ccccc1
    Show/Hide
Compound Formula C16H17N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 20 nM
   TI
   LI
   LO
   TS
2
Ki = 4.2 nM
   TI
   LI
   LO
   TS