Brief Information of the Compound and Protein
Compound Name
2-(3-{[3-(Trifluoromethyl)phenyl]sulfonyl}-1Hpyrrolo[2,3-b]pyridin-1-yl)ethylamine
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PubChem ID
CID: 45484384
Canonical SMILES
NCCn1cc(c2cccnc12)S(=O)(=O)c1cccc(c1)C(F)(F)F
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Compound Formula C16H14F3N3O2S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa Homo sapiens (Human)  2
1
EC50 = 110 nM
   TI
   LI
   LO
   TS
2
Ki = 2.1 nM
   TI
   LI
   LO
   TS