Brief Information of the Compound and Protein
Compound Name
5-(4-Methylpiperazin-1-yl)pentanoic acid(4-pyridin-3-ylphenyl)amide
    Show/Hide
PubChem ID
CID: 45484338
Canonical SMILES
CN1CCN(CCCCC(=O)Nc2ccc(cc2)-c2cccnc2)CC1
    Show/Hide
Compound Formula C21H28N4O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Nicotinic acetylcholine receptor
>
Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
Q05941
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000029 GH4C1 Rattus norvegicus (Rat)  1
1
EC50 = 3560 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 9330 nM
   TI
   LI
   LO
   TS