Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-(3-(4-methoxybenzyl)phenyl)-8-phenyl-2,3,4,8-tetrahydroimidazo[1,5-a]pyrimidin-6-amine
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 PubChem ID
CID: 11618427
SID: 16721356
Canonical SMILES
COc1ccc(Cc2cccc(c2)C2(N=C(N)N3CCCN=C23)c2ccccc2)cc1
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Compound Formula C26H26N4O
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 1
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
P56817
Gene Name
BACE1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 5100 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 7100 nM