Brief Information of the Compound and Protein
Compound Name
2-(6-{[(6-chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonyl](methyl)amino}-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide hydrochloride
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PubChem ID
CID: 44474796
SID: 85755252
Canonical SMILES
CN(c1ccc2c(c1)/C(=N/NC(=N)N)CC2)S(=O)(=O)c1c(Cl)nc2sccn12.Cl
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Compound Formula C16H17Cl2N7O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 4.1 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 54 nM
   TI
   LI
   LO
   TS