Brief Information of the Compound and Protein
Compound Name
6-chloro-N-[3-(4,5-dihydro-1H-imidazol-2-ylhydrazono)-2,3-dihydro-1H-inden-5-yl]imidazo[2,1-b][1,3]thiazole-5-sulfonamide
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PubChem ID
CID: 45483622
Canonical SMILES
Clc1nc2sccn2c1S(=O)(=O)Nc1ccc2CC\C(=N/NC3=NCCN3)c2c1
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Compound Formula C17H16ClN7O2S2
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 176 nM
   TI
   LI
   LO
   TS