Brief Information of the Compound and Protein
Compound Name
2-(6-{[(4-methyl-3,4-dihydro-2H-1,4-benzoxazine-7-yl)sulfonyl]amino}-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide hydrochloride
    Show/Hide
PubChem ID
CID: 44474469
SID: 85754922
Canonical SMILES
CN1CCOc2ccc(S(=O)(=O)Nc3ccc4c(c3)/C(=N/NC(=N)N)CC4)cc21.Cl
    Show/Hide
Compound Formula C19H23ClN6O3S
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 26 nM
   TI
   LI
   LO
   TS
CL000131 HEK293-F Homo sapiens (Human)  1
1
IC50 = 581 nM
   TI
   LI
   LO
   TS