Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-[3-({(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazin-1-yl}sulfonyl)phenyl]pyrrolidine-3-carboxylic acid
    Show/Hide
 PubChem ID
CID: 24906193
SID: 53800367
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(c1)N1CCC(C1)C(O)=O)c1ccc(F)cc1C(F)(F)F
    Show/Hide
Compound Formula C23H25F4N3O4S
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 160 nM
   TI
   LI
   LO
   TS