Brief Information of the Compound and Protein
Compound Name
(2R)-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methyl-1-{[3-(1H-pyrazol-1-yl)phenyl]sulfonyl}piperazine
    Show/Hide
PubChem ID
CID: 24906239
SID: 53800427
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1cccc(c1)-n1ccnc1)c1ccc(F)cc1C(F)(F)F
    Show/Hide
Compound Formula C21H20F4N4O2S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P28845
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 74 nM
   TI
   LI
   LO
   TS