Brief Information of the Compound and Protein
Compound Name
(S) -2-amino-3-[4-(2-amino-6-[2,2,2-trifluoro-1-(2-(3-trifluoromethyl-pyrazol-1-yl-phenyl)-ethoxy]-pyrimidin-4-yl]-phenyl-propionic acid
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PubChem ID
CID: 24894761
SID: 53778954
Canonical SMILES
N[C@@H](Cc1ccc(cc1)-c1cc(OC(c2ccccc2-n2ccc(n2)C(F)(F)F)C(F)(F)F)nc(N)n1)C(O)=O
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Compound Formula C25H20F6N6O3
Compound Structure
Protein Name
Tryptophan 5-hydroxylase 2
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
Q8IWU9
Gene Name
TPH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000592 BON Homo sapiens (Human)  1
1
EC50 = 750 nM
   TI
   LI
   LO
   TS