Brief Information of the Compound and Protein
Compound Name
 Compound Info 
42-548
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 PubChem ID
CID: 4020
SID: 99431540
Canonical SMILES
OC1(N2CCN=C2c2ccccc12)c1ccc(Cl)cc1
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Compound Formula C16H13ClN2O
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent dopamine transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
Q01959
Gene Name
SLC6A3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  4
1
Activity = 22.1 nM
   TI
   LI
   LO
   TS
2
IC50 = 22 nM
   TI
   LI
   LO
   TS
3
IC50 = 22.1 nM
   TI
   LI
   LO
   TS
4
Ki = 22.1 nM
   TI
   LI
   LO
   TS
CL001018 HEK-hDAT
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 45 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  5
1
IC50 = 13 nM
   TI
   LI
   LO
   TS
2
IC50 = 43 nM
   TI
   LI
   LO
   TS
3
Ki = 34.6 nM
   TI
   LI
   LO
   TS
4
Ki = 45 nM
   TI
   LI
   LO
   TS
5
Ki = 74.2 nM
   TI
   LI
   LO
   TS