Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8-(1-(1-methylpyrrolidin-3-yl)-1H-indol-3-ylsulfonyl)quinoline
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 PubChem ID
CID: 46880759
Canonical SMILES
CN1CCC(C1)n1cc(c2ccccc12)S(=O)(=O)c1cccc2cccnc12
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Compound Formula C22H21N3O2S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000017 HeLa
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 76 nM
   TI
   LI
   LO
   TS
2
Ki = 2.8 nM
   TI
   LI
   LO
   TS