Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-4-(3-(isoquinolin-6-yl)isoxazol-5-yl)-1-(4-(trifluoromethyl)phenyl)butan-2-amine
    Show/Hide
 PubChem ID
CID: 46880294
Canonical SMILES
N[C@H](CCc1cc(no1)-c1ccc2cnccc2c1)Cc1ccc(cc1)C(F)(F)F
    Show/Hide
Compound Formula C23H20F3N3O
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3800 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 40 nM