Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(S)-N1-(5-(3-aminoisoquinolin-6-yl)thiazol-2-yl)-3-(4-(trifluoromethyl)phenyl)propane-1,2-diamine
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 PubChem ID
CID: 23654594
SID: 46526863
Canonical SMILES
N[C@H](CNc1ncc(s1)-c1ccc2cnc(N)cc2c1)Cc1ccc(cc1)C(F)(F)F
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Compound Formula C22H20F3N5S
Compound Structure
Protein Name
 Protein Info 
RAC-alpha serine/threonine-protein kinase
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
AGC protein kinase group
>
AGC protein kinase AKT family
Uniprot ID
P31749
Gene Name
AKT1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000102 U-87MG ATCC
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 890 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 11.6 nM