Brief Information of the Compound and Protein
Compound Name
2-((1-(6-(benzo[b]thiophen-2-yl)pyrimidin-4-yl)piperidin-4-yl)methoxy)-5-fluoropyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 46879631
Canonical SMILES
Nc1nc(OCC2CCN(CC2)c2cc(ncn2)-c2cc3ccccc3s2)ncc1F
    Show/Hide
Compound Formula C22H21FN6OS
Compound Structure
Protein Name
Deoxycytidine kinase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P27707
Gene Name
DCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  1
1
EC50 = 790 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 34 nM