Brief Information of the Compound and Protein
Compound Name
2-(1-(6-(2-ethylphenoxy)pyrimidin-4-yl)piperidin-4-yloxy)-5-fluoropyrimidin-4-amine
    Show/Hide
PubChem ID
CID: 25026090
SID: 56376753
Canonical SMILES
CCc1ccccc1Oc1cc(ncn1)N1CCC(CC1)Oc1ncc(F)c(N)n1
    Show/Hide
Compound Formula C21H23FN6O2
Compound Structure
Protein Name
Deoxycytidine kinase
Protein Classification
Enzyme
>
Transferase
Uniprot ID
P27707
Gene Name
DCK
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000108 CCRF-CEM Homo sapiens (Human)  1
1
EC50 = 61 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 10 nM