Brief Information of the Compound and Protein
Compound Name
(+/-)-SKF-38393
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PubChem ID
CID: 1242
SID: 12013073
Canonical SMILES
Oc1cc2CCNCC(c3ccccc3)c2cc1O
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Compound Formula C16H17NO2
Compound Structure
Protein Name
D(1A) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21728
Gene Name
DRD1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000026 CHO-K1 Cricetulus griseus (Chinese hamster)  1
1
EC50 = 665.9 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  3
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
2
EC50 = 300 nM
   TI
   LI
   LO
   TS
3
Ki = 393 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 247.5 nM