Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(R)-3-(1-(2-chloro-4-((dimethylamino)methyl)phenyl)ethoxy)-5-(imidazo[1,2-a]pyridin-3-yl)thiophene-2-carboxamide
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 PubChem ID
CID: 45272066
Canonical SMILES
C[C@@H](Oc1cc(sc1C(N)=O)-c1cnc2ccccn12)c1ccc(CN(C)C)cc1Cl
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Compound Formula C23H23ClN4O2S
Compound Structure
Protein Name
 Protein Info 
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
>
Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000162 HeLa S3
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 48000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM