Brief Information of the Compound and Protein
Compound Name
5-(imidazo[1,2-a]pyridin-3-yl)-3-(2-(trifluoromethyl)benzyloxy)thiophene-2-carboxamide
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PubChem ID
CID: 45273806
Canonical SMILES
NC(=O)c1sc(cc1OCc1ccccc1C(F)(F)F)-c1cnc2ccccn12
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Compound Formula C20H14F3N3O2S
Compound Structure
Protein Name
Serine/threonine-protein kinase PLK1
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
Other protein kinase group
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Other protein kinase PLK family
Uniprot ID
P53350
Gene Name
PLK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000162 HeLa S3 Homo sapiens (Human)  1
1
EC50 = 5000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 22 nM