Brief Information of the Compound and Protein
Compound Name
4-N-(2,3-dihydro-1H-inden-2-yl)-6-N-[2-(dimethylamino)ethyl]pyrido[3,4-d]pyrimidine-4,6-diamine
    Show/Hide
PubChem ID
CID: 44592030
Canonical SMILES
CN(C)CCNc1cc2c(NC3Cc4ccccc4C3)ncnc2cn1
    Show/Hide
Compound Formula C20H24N6
Compound Structure
Protein Name
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
>
Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
>
Metabotropic glutamate receptor
Uniprot ID
P23385
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
Ki = 102 nM
   TI
   LI
   LO
   TS