Brief Information of the Compound and Protein
Compound Name
(S)-7-[(Benzyl-methyl-amino)-methyl]-3-methoxy-5,6,7,8-tetrahydro-10-thia-5,8-diaza-benzo[a]azulen-9-one
    Show/Hide
PubChem ID
CID: 45269365
Canonical SMILES
COc1ccc2sc3c(NC[C@@H](CN(C)Cc4ccccc4)NC3=O)c2c1
    Show/Hide
Compound Formula C21H23N3O2S
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 24000 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 1910 nM