Brief Information of the Compound and Protein
Compound Name
(R)-3-(2-Methoxy-phenyl)-10-methyl-9,10,11,12-tetrahydro-7-thia-4,9,12-triaza-naphtho[1,2-a]azulen-8-one
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PubChem ID
CID: 45268471
Canonical SMILES
COc1ccccc1-c1ccc2c3c4NC[C@@H](C)NC(=O)c4sc3ccc2n1
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Compound Formula C22H19N3O2S
Compound Structure
Protein Name
MAP kinase-activated protein kinase 2
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
CAMK protein kinase group
>
CAMK protein kinase MAPKAPK family
>
CAMK protein kinase MAPKAPK subfamily
Uniprot ID
P49137
Gene Name
MAPKAPK2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000100 U-937 Homo sapiens (Human)  1
1
IC50 = 1040 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 20 nM