Brief Information of the Compound and Protein
Compound Name
N-(2-cyclopropyl-3-methylimidazo[1,2-a]pyridin-6-yl)-5-(4-fluorophenyl)pyrazine-2-carboxamide
    Show/Hide
PubChem ID
CID: 23120550
Canonical SMILES
Cc1c(nc2ccc(NC(=O)c3cnc(cn3)-c3ccc(F)cc3)cn12)C1CC1
    Show/Hide
Compound Formula C22H18FN5O
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 70 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 2.5 nM