Brief Information of the Compound and Protein
Compound Name
Benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-but-2-enyl}-amide
    Show/Hide
PubChem ID
CID: 11351639
SID: 16443312
Canonical SMILES
Clc1cccc(N2CCN(C\C=C\CNC(=O)c3cc4ccccc4s3)CC2)c1Cl
    Show/Hide
Compound Formula C23H23Cl2N3OS
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  2
1
IC50 = 9.62 nM
   TI
   LI
   LO
   TS
2
Ki = 1.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1.1 nM