Brief Information of the Compound and Protein
Compound Name
N-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]-3-hydroxybutyl]-1-benzofuran-2-carboxamide
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PubChem ID
CID: 42625290
SID: 81058466
Canonical SMILES
OC(CCNC(=O)c1cc2ccccc2o1)CN1CCN(CC1)c1cccc(Cl)c1Cl
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Compound Formula C23H25Cl2N3O3
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  4
1
EC50 = 22.8 nM
   TI
   LI
   LO
   TS
2
IC50 = 13.7 nM
   TI
   LI
   LO
   TS
3
Ki = 0.98 nM
   TI
   LI
   LO
   TS
4
Ki = 6.11 nM
   TI
   LI
   LO
   TS