Brief Information of the Compound and Protein
Compound Name
(R)-N-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)-3-hydroxybutyl)-1H-indole-2-carboxamide
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PubChem ID
CID: 42626318
SID: 81058614
Canonical SMILES
O[C@H](CCNC(=O)c1cc2ccccc2[nH]1)CN1CCN(CC1)c1cccc(Cl)c1Cl
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Compound Formula C23H26Cl2N4O2
Compound Structure
Protein Name
D(3) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P35462
Gene Name
DRD3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  3
1
IC50 = 18.2 nM
   TI
   LI
   LO
   TS
2
Ki = 0.53 nM
   TI
   LI
   LO
   TS
3
Ki = 1.12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 0.53 nM
2 Ki = 2.9 nM