Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,5-difluoro-N-(4-(trifluoromethyl)oxazol-2-yl)-9H-xanthene-9-carboxamide
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 PubChem ID
CID: 44573780
Canonical SMILES
Fc1cccc2C(C(=O)Nc3nc(co3)C(F)(F)F)c3cccc(F)c3Oc12
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Compound Formula C18H9F5N2O3
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 1
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
>
Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P23385
Gene Name
GRM1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 161 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 47 nM
   TI
   LI
   LO
   TS