Brief Information of the Compound and Protein
Compound Name
cis-5-(2-(2-chlorophenyl)thiazol-5-yl)-1-methyl-3-(piperidin-1-ylmethyl)pyrrolidin-2-one
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PubChem ID
CID: 44565210
Canonical SMILES
CN1C(=O)[C@@H](CN2CCCCC2)C[C@H]1c1cnc(-c2ccccc2Cl)s1
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Compound Formula C20H24ClN3OS
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000033 GH3 Rattus norvegicus (Rat)  1
1
EC50 = 25.12 nM
   TI
   LI
   LO
   TS