Brief Information of the Compound and Protein
Compound Name
(3E)-3-[(2,4-DIMETHOXYPHENYL)METHYLIDENE]-3,4,5,6-TETRAHYDRO-2,3'-BIPYRIDINE
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PubChem ID
CID: 5310985
SID: 14898738
Canonical SMILES
COc1ccc(\C=C2/CCCN=C2c2cccnc2)c(OC)c1
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Compound Formula C19H20N2O2
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000033 GH3 Rattus norvegicus (Rat)  1
1
EC50 = 1995.26 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 158 nM