Brief Information of the Compound and Protein
Compound Name
(3R,5S)-1-methyl-5-(2-phenylethynyl)-3-(piperidin-1-ylmethyl)pyrrolidin-2-one
    Show/Hide
PubChem ID
CID: 42631007
SID: 81069980
Canonical SMILES
CN1[C@@H](C[C@H](CN2CCCCC2)C1=O)C#Cc1ccccc1
    Show/Hide
Compound Formula C19H24N2O
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
>
Ligand-gated ion channel
>
Nicotinic acetylcholine receptor
>
Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000033 GH3 Rattus norvegicus (Rat)  1
1
EC50 = 10 nM
   TI
   LI
   LO
   TS