Brief Information of the Compound and Protein
Compound Name
(-)-Spiro[1-azabicyclo(2.2.2)octane-3,5'-oxazolidin-2'-one]
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PubChem ID
CID: 5310971
SID: 26683769
Canonical SMILES
O=C1NC[C@@]2(CN3CCC2CC3)O1
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Compound Formula C9H14N2O2
Compound Structure
Protein Name
Neuronal acetylcholine receptor subunit alpha-7
Protein Classification
Ion channel
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Ligand-gated ion channel
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Nicotinic acetylcholine receptor
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Nicotinic acetylcholine receptor alpha subunit
Uniprot ID
P36544
Gene Name
CHRNA7
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000033 GH3 Rattus norvegicus (Rat)  1
1
EC50 = 398.11 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 92 nM
2 Ki = 92 nM
3 Ki = 340 nM
4 Ki = 420 nM