Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[4-[6-chloro-3-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]-5-methoxy-1-methylbenzimidazole
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 PubChem ID
CID: 46225385
Canonical SMILES
COc1ccc2n(C)c(CN3CCN(CC3)c3nc(Cl)ccc3C(F)(F)F)nc2c1
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Compound Formula C20H21ClF3N5O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
EC50 = 251.19 nM
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