Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-[[4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperidin-1-yl]methyl]-1-methylbenzimidazole
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 PubChem ID
CID: 46225584
Canonical SMILES
Cn1c(CN2CCC(CC2)c2ncc(cc2Cl)C(F)(F)F)nc2ccccc12
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Compound Formula C20H20ClF3N4
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 39.81 nM
   TI
   LI
   LO
   TS
2
EC50 = 630.96 nM
   TI
   LI
   LO
   TS