Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-methyl-2-[[4-[5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl]methyl]benzimidazole
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 PubChem ID
CID: 46225337
Canonical SMILES
Cn1c(CN2CCN(CC2)c2ccc(cn2)C(F)(F)F)nc2ccccc12
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Compound Formula C19H20F3N5
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
EC50 = 501.19 nM
   TI
   LI
   LO
   TS
2
EC50 = 6309.57 nM
   TI
   LI
   LO
   TS