Brief Information of the Compound and Protein
Compound Name
1-methyl-2-[[4-[3-(trifluoromethyl)phenyl]piperidin-1-yl]methyl]benzimidazole
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PubChem ID
CID: 24815883
SID: 49815081
Canonical SMILES
Cn1c(CN2CCC(CC2)c2cccc(c2)C(F)(F)F)nc2ccccc12
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Compound Formula C21H22F3N3
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
>
Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 100 nM
   TI
   LI
   LO
   TS
2
EC50 = 2511.89 nM
   TI
   LI
   LO
   TS